Resolution of 2-phenoxy-1-propanols by Pseudomonas sp. lipase-catalyzed highly enantioselective transesterification:: influence of reaction conditions on the enantioselectivity toward primary alcohols

被引：15

作者：

Miyazawa, T ^{[1
]}

Yukawa, T

Ueji, S

Yanagihara, R

Yamada, T

机构：

[1] Konan Univ, Fac Sci, Dept Chem, Higashinada Ku, Kobe, Hyogo 658, Japan

[2] Kobe Univ, Fac Human Dev & Sci, Div Nat Environm & Bioorgan Chem, Nada Ku, Kobe, Hyogo 657, Japan

来源：

BIOTECHNOLOGY LETTERS | 1998年 / 20卷 / 03期

关键词：

D O I：

10.1023/A:1005317600475

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

2-Phenoxy-1-propanols were resolved using Pseudomonas sp. lipase with E (enantiomeric ratio) values of greater than or equal to 15. The enantioselectivity was highest with vinyl acetate and became lower with the chain length of the fatty acid moiety of acyl donors. It was improved with decreasing temperature. A linear direct correlation was observed between -RTlnE and the temperature of the reaction.

引用

页码：235 / 238

页数：4

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