Conjugated polyelectrolytes as fluorescent sensors

被引：162

作者：

Liu, Yan ^{[1
]}

Ogawa, Katsu ^{[1
]}

Schanze, Kirk S. ^{[1
]}

机构：

[1] Univ Florida, Dept Chem, Gainesville, FL 32611 USA

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS | 2009年 / 10卷 / 04期

关键词：

Conjugated polymer; Conjugated polyelectrolyte; Fluorescence; Sensor; Biosensor; Quenching; SOLUBLE POLY(PHENYLENE ETHYNYLENE); HIGHLY SENSITIVE DETECTION; MOLECULAR WIRE APPROACH; ENERGY-TRANSFER; POLYMER FLUORESCENCE; OPTICAL PROBES; DNA DETECTION; CHAIN-LENGTH; AGGREGATION; PHOTOLUMINESCENCE;

D O I：

10.1016/j.jphotochemrev.2009.10.003

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Conjugated polyelectrolytes (CPEs) have become one of the most utilized materials in chemo- and bio-sensory systems. Useful properties of CPEs, such as amplified quenching effects and aggregation behavior, are illustrated in detail in order to provide guidelines for underlying concepts of CPE-based sensors. Well established sensing mechanisms, such as conformational changes and fluorescence resonance energy transfer, are reviewed with representative examples. Target species include small ions, small biomolecules, proteins, enzymatic activities, and DNA. New and unique mechanisms for CPE-based sensing are also described. (C) 2009 Elsevier B.V. All rights reserved.

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收藏

页码：173 / 190

页数：18

相关论文

共 115 条

[1] Tuning the photophysical properties of an ionic conjugated polymer through interactions with conventional polyelectrolytes [J].

Abe, S ;

Chen, LH .

JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS, 2003, 41 (14) :1676-1679

[2] Fluorescence superquenching of conjugated polyelectrolytes: applications for biosensing and drug discovery [J].

Achyuthan, KE ;

Bergstedt, TS ;

Chen, L ;

Jones, RM ;

Kumaraswamy, S ;

Kushon, SA ;

Ley, KD ;

Lu, L ;

McBranch, D ;

Mukundan, H ;

Rininsland, F ;

Shi, X ;

Xia, W ;

Whitten, DG .

JOURNAL OF MATERIALS CHEMISTRY, 2005, 15 (27-28) :2648-2656

[3] Design and synthesis of novel glycopolythiophene assemblies for colorimetric detection of influenza virus and E-coli [J].

Baek, MG ;

Stevens, RC ;

Charych, DH .

BIOCONJUGATE CHEMISTRY, 2000, 11 (06) :777-788

[4] Conjugated polythiophene probes target lysosome-related acidic vacuoles in cultured primary cells [J].

Bjork, Per ;

Nilsson, K. Peter R. ;

Lenner, Liselotte ;

Kagedal, Bertil ;

Persson, Birgitta ;

Inganas, Olle ;

Jonasson, Jon .

MOLECULAR AND CELLULAR PROBES, 2007, 21 (5-6) :329-337

[5] SENSITIVE FLUORESCENT DETERMINATION OF TRYPSIN-LIKE PROTEASES [J].

BROWN, F ;

FREEDMAN, ML ;

TROLL, W .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1973, 53 (01) :75-81

[6] Poly(aryleneethynylene)s: Syntheses, properties, structures, and applications [J].

Bunz, UHF .

CHEMICAL REVIEWS, 2000, 100 (04) :1605-1644

[7] Conjugated Polyelectrolyte Supported Bead Based Assays for Phospholipase A2 Activity [J].

Chemburu, Sireesha ;

Ji, Eunkyung ;

Casana, Yosune ;

Wu, Yang ;

Buranda, Tione ;

Schanze, Kirk S. ;

Lopez, Gabriel P. ;

Whitten, David G. .

JOURNAL OF PHYSICAL CHEMISTRY B, 2008, 112 (46) :14492-14499

[8] Highly sensitive biological and chemical sensors based on reversible fluorescence quenching in a conjugated polymer [J].

Chen, LH ;

McBranch, DW ;

Wang, HL ;

Helgeson, R ;

Wudl, F ;

Whitten, DG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (22) :12287-12292

[9] Surfactant-induced modification of quenching of conjugated polymer fluorescence by electron acceptors: applications for chemical sensing [J].

Chen, LH ;

McBranch, D ;

Wang, R ;

Whitten, D .

CHEMICAL PHYSICS LETTERS, 2000, 330 (1-2) :27-33

[10] Tuning the properties of conjugated polyelectrolytes through surfactant complexation [J].

Chen, LH ;

Xu, S ;

McBranch, D ;

Whitten, D .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (38) :9302-9303

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