Emerging themes in medicinal glycoscience

被引:139
作者
Koeller, KM
Wong, CH
机构
[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA
[2] Skaggs Inst Chem Biol, La Jolla, CA 92037 USA
关键词
glycoconjugate; synthesis; therapeutic; antibiotic; vaccine;
D O I
10.1038/78435
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The recognition of complex carbohydrates and glycoconjugates as mediators of important biological processes has stimulated investigation into their therapeutic potential. New approaches for the simplification of glycoconjugate synthesis are overcoming the limitations of existing methods and providing a diverse array of these biomolecules. As the accessibility of glycoconjugates increases, carbohydrate-based constructs are becoming available for analysis as medicinal agents in a wide range of therapies.
引用
收藏
页码:835 / 841
页数:7
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