New homogeneously and heterogeneously [Pd/Cu]-catalysed C3-alkenylation of free NH-indoles

被引：53

作者：

Djakovitch, Laurent ^{[1
]}

Rouge, Pascal ^{[1
]}

机构：

[1] Univ Lyon 1, IRCELYON, Inst Rech Catalyse & Environm Lyon, UMR 5256 CNRS, F-69626 Villeurbanne, France

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2007年 / 273卷 / 1-2期

关键词：

3-vinyl indoles; oxidative coupling; palladium-copper catalysts; zeolites;

D O I：

10.1016/j.molcata.2007.04.011

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A new palladium/copper catalytic procedure for the C-3-alkenylation of free NH-indoles is reported. Using homogeneous or heterogeneous hetero-bimetallic [Pd/Cu] -catalysts under mild reaction conditions (10 mol% Pd-catalyst and 10 mol% Cu-catalyst, 70 degrees C, air), substituted indoles are fully (58-82% isolated yields) and selectively (75-100% selectivity) converted to the expected 2-substituted-3-vinyl indoles. (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：230 / 239

页数：10

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