Value of 124I-PET/CT in staging of patients with differentiated thyroid cancer

被引：83

作者：

Freudenberg, LS

Antoch, G

Jentzen, W

Pink, R

Knust, J

Görges, R

Müller, SP

Bockisch, A

Debatin, JF

Brandau, W

机构：

[1] Univ Essen Gesamthsch, Clin & Policlin Nucl Med, D-45122 Essen, Germany

[2] Univ Essen Gesamthsch, Dept Radiol, Essen, Germany

来源：

EUROPEAN RADIOLOGY | 2004年 / 14卷 / 11期

关键词：

dual-modality; thyroid cancer; staging; PET; PET/CT; iodine-124; iodine-131; WBS;

D O I：

10.1007/s00330-004-2350-0

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The aim of this study is to evaluate the clinical significance of I-124 positron emission tomography (PET) using a combined PET/CT tomograph in patients with differentiated thyroid carcinoma and to compare the PET/CT results with I-131 whole-body scintigraphy (WBS), dedicated PET and CT alone, Twelve thyroid cancer patients were referred for diagnostic workup and entered complete clinical evaluation, including histology, cytology, thyroglobulin level, ultrasonography, fluorine-18 fluorodeoxyglucose (FDG)-PET, FDG-PET/CT and CT. Lesion-based evaluation showed a lesion delectability of 56, 87 and 100% for CT, I-124-PET, and combined I-124-PET/CT imaging, respectively. Lesion delectability of I-131-WBS was 83%. We conclude that I-124-PET/CT imaging is a promising technique to improve treatment planning in thyroid cancer. It is particularly valuable in patients suffering from advanced differentiated thyroid cancer prior to radio-iodine therapy and in patients with suspected recurrence and potential metastatic disease.

引用

页码：2092 / 2098

页数：7

共 24 条

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