共 47 条
Pd-catalyzed amination of nucleoside arylsulfonates to yield N6-aryl-2,6-diaminopurine nucleosides
被引:52
作者:

Gunda, P
论文数: 0 引用数: 0
h-index: 0
机构: CUNY City Coll, Dept Chem, New York, NY 10031 USA

Russon, LM
论文数: 0 引用数: 0
h-index: 0
机构: CUNY City Coll, Dept Chem, New York, NY 10031 USA

Lakshman, MK
论文数: 0 引用数: 0
h-index: 0
机构: CUNY City Coll, Dept Chem, New York, NY 10031 USA
机构:
[1] CUNY City Coll, Dept Chem, New York, NY 10031 USA
[2] Analyt Branford Inc, Branford, CT 06405 USA
关键词:
amination;
C-C coupling;
nucleosides;
palladium;
phosphane ligands;
D O I:
10.1002/anie.200460782
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
(Chemical equation presented). Substituents on both the nucleoside arylsulfonate as well as the aryl amine component have a significant impact on their coupling to form 2,6-diaminopurine-2′-deoxyribonucleosides (see scheme). A systematic study of ligands for the Pd catalysts in amination and C-C cross-coupling reactions gives insight into the structural elements that lead to effective catalysis.
引用
收藏
页码:6372 / 6377
页数:6
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