Copper-catalyzed anti-stereocontrolled ring-opening of azabicyclic alkenes with grignard reagents

被引：57

作者：

Arrayás, RG ^{[1
]}

Cabrera, S ^{[1
]}

Carretero, JC ^{[1
]}

机构：

[1] Univ Autonoma Madrid, Fac Ciencias, Dept Quim Organ, E-28049 Madrid, Spain

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 02期

关键词：

D O I：

10.1021/ol0478133

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The anti-stereocontrolled alkylative ring-opening reaction of azabicyclic alkenes is reported. N(2-Plyridyl)sutfonyl azabenzonorblomadiene reacts with Grignard reagents in the presence of catalytic amounts of CuCN to afford, in good yields and excellent anti selectivity, the corresponding dihydronaphthalene-1-amines.

引用

页码：219 / 221

页数：3

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