ALPHA-AMINO ESTER DERIVATIVES AS NUCLEOPHILES IN STEREOSELECTIVE PALLADIUM-CATALYZED ALLYLIC SUBSTITUTION-REACTIONS

被引：44

作者：

BALDWIN, IC

WILLIAMS, JMJ

BECKETT, RP

机构：

[1] LOUGHBOROUGH UNIV TECHNOL,DEPT CHEM,LOUGHBOROUGH LE11 3TU,LEICS,ENGLAND

[2] BRIT BIOTECH PHARMACEUT LTD,OXFORD OX4 5LY,ENGLAND

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 07期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/0957-4166(95)00186-S

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The stereoselective palladium catalysed reaction between allyl acetates and imino esters is reported. For suitable substrates, diastereoselectivities are good (up to 84:16), and in the presence of enantiomerically pure pbosphorus-containing oxazoline ligands, the enantioselectivities (up to 97% ee) are very high.

引用

页码：1515 / 1518

页数：4

共 18 条

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