HIGHLY SELECTIVE AND PRACTICAL ALKYNE-ALKYNE CROSS-COUPLING USING CP(2)ZRBU(2) AND ETHYLENE

被引：138

作者：

XI, ZF

HARA, R

TAKAHASHI, T

机构：

[1] INST MOLEC SCI,COORDINAT CHEM LABS,OKAZAKI,AICHI 444,JAPAN

[2] GRAD UNIV ADV STUDIES,OKAZAKI,AICHI 444,JAPAN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1995年 / 60卷 / 14期

关键词：

D O I：

10.1021/jo00119a022

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Highly selective alkyne-alkyne cross coupling reactions were achieved using Cp(2)ZrBu(2) and ethylene gas. First, alkynes were treated with 1.2 equiv of Cp(2)ZrBu(2) (Negishi reagent) under ethylene gas to give zirconacyclopentenes with high selectivities. Subsequent addition of a second alkyne to the solution of zirconacyclopentenes at 50 degrees C gave unsymmetrical zirconacyclopentadienes selectively. After hydrolysis unsymmetrical dienes were obtained in high yields.

引用

页码：4444 / 4448

页数：5

共 44 条

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