QUINAZOLINE ANTIFOLATE THYMIDYLATE SYNTHASE INHIBITORS - NITROGEN, OXYGEN, SULFUR, AND CHLORINE SUBSTITUENTS IN THE C2 POSITION

被引：22

作者：

MARSHAM, PR ^{[1
]}

CHAMBERS, P ^{[1
]}

HAYTER, AJ ^{[1
]}

HUGHES, LR ^{[1
]}

JACKMAN, AL ^{[1
]}

OCONNOR, BM ^{[1
]}

BISHOP, JAM ^{[1
]}

CALVERT, AH ^{[1
]}

机构：

[1] INST CANC RES, SUTTON SM2 5NG, SURREY, ENGLAND

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 03期

关键词：

D O I：

10.1021/jm00123a010

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：569 / 575

页数：7

共 21 条

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[14] QUINAZOLINE ANTIFOLATES INHIBITING THYMIDYLATE SYNTHASE - VARIATION OF THE AMINO-ACID
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (06) : 1114 - 1118
[15] QUINAZOLINE ANTIFOLATES INHIBITING THYMIDYLATE SYNTHASE - BENZOYL RING MODIFICATIONS
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[16] Quinazolines V The partial hydrolysis of 2,4-dialkoxy-quinazolines with the formation of 2-alkoxy-4-ketodihydroquinazolines
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[17] NEWELL DR, 1982, P AM ASSOC CANC RES, V23, P181
[18] NEWELL DR, 1986, CANCER TREAT REP, V70, P971
[19] POLYAZANAPHTHALENES .7. SOME DERIVATIVES OF QUINAZOLINE AND 1,3,5-TRIAZANAPHTHALENE
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[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1962, (NOV): : 4678 - &
[20] FORMATION AND RETENTION AND BIOLOGICAL-ACTIVITY OF N10-PROPARGYL-5,8-DIDEAZAFOLIC ACID (CB3717) POLYGLUTAMATES IN L1210 CELLS-INVITRO
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[J]. BIOCHEMICAL PHARMACOLOGY, 1988, 37 (21) : 4047 - 4054

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