NUCLEIC-ACID MIMICS - SYNTHESIS OF ETHYLENE GLYCOL-LINKED AND PROPOXY-LINKED THYMIDYL-TETRAHYDROFURANYLTHYMINE DIMERS VIA A VORBRUGGEN-TYPE GLYCOSYLATION REACTION

被引：18

作者：

TENG, K

COOK, PD

机构：

[1] Department of Medicinal Chemistry, ISIS Pharmaceuticals, Carlsbad, California 92008

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 02期

关键词：

D O I：

10.1021/jo00081a003

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two thymidyl-tetrahydrofuranylthymine dimers, 15 and 16, were synthesized stereospecifically in good yield via a Vorbruggen-type reaction between glycol ether 4 or propoxy alcohol 7 and acetate 12.

引用

页码：278 / 280

页数：3

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