ETA(5)-PENTAMETHYLCYCLOPENTADIENYLRUTHENIUM(II) COMPLEXES CONTAINING ETA(6)-CO-ORDINATED DIPEPTIDES WITH AROMATIC SIDE-CHAINS

被引：57

作者：

GLEICHMANN, AJ ^{[1
]}

WOLFF, JM ^{[1
]}

SHELDRICK, WS ^{[1
]}

机构：

[1] RUHR UNIV BOCHUM,LEHRSTUHL ANALYT CHEM,D-44780 BOCHUM,GERMANY

来源：

JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS | 1995年 / 10期

关键词：

D O I：

10.1039/dt9950001549

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The eta(6)-co-ordinated amino acid complexes [RU(eta(5)-C(5)Me(5))(eta(6)-HaaOH)][CF3SO3] [HaaOH = L-HPheOH (phenylalanine) or L-HTrpOH (tryptophan)] were prepared by reaction of [Ru(eta(5)-C(5)Me(5))(MeCN)(3)][CF3SO3] with the relevant amino acid in tetrahydrofuran. Dipeptide complexes of the type [{Ru(eta(5)-C(3)Me(5))}(2)(mu-eta(6):eta(6)-pep)][CF3SO3](2) [pep = HPhe-PheOH, cyclo(-Phe-Phe-), HTrp-TrpOH, or cyclo(-Trp-Trp-)] may be obtained under analogous conditions. Ultraviolet irradiation of [{RU(eta(5)-C(5)Me(5))}(2){cyclo(-Phe-Phe-)}][CF3SO3](2) leads to photochemical release of cyclo(-Phe-Phe-) in quantitative yield. The feasibility of peptide synthesis from individual amino acid complexes was demonstrated by the preparation of [Ru(eta(5)-C(5)Me(5)){eta(6)-cyclo(-Phe-Phe-)}]Cl from [Ru(eta(5)-C(5)Me(5))(eta(6)-L-HPhe-OMe)]Cl by the carbodiimide method. A crystal structure analysis was carried out for[{Ru(eta(5)-C(5)Me(5))}(2){cyclo(-Phe-Phe-)}][CF3SO3](2).

引用

页码：1549 / 1554

页数：6

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