BIOLOGICAL-ACTIVITY OF SOME COUMARINS FROM SRI-LANKAN RUTACEAE

被引：64

作者：

GUNATILAKA, AAL

KINGSTON, DGI

WIJERATNE, EMK

BANDARA, BMR

HOFMANN, GA

JOHNSON, RK

机构：

[1] UNIV PERADENIYA,DEPT CHEM,PERADENIYA,SRI LANKA

[2] SMITHKLINE BEECHAM PHARMACEUT,RES & DEV,KING OF PRUSSIA,PA 19406

来源：

JOURNAL OF NATURAL PRODUCTS | 1994年 / 57卷 / 04期

关键词：

D O I：

10.1021/np50106a013

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Twelve coumarins isolated from plants of the Rutaceae collected in Sri Lanka have been subjected to a mechanism-based anticancer bioassay employing DNA repair-deficient and repair-proficient yeasts. Of these, seselin [10] and xanthyletin [11] were found to be active. Seselin also exhibited moderate cytotoxicity.

引用

页码：518 / 520

页数：3

共 16 条

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