BUILDING-BLOCKS FOR ARTIFICIAL ANION RECEPTORS - DERIVATIVES OF CHIRAL BICYCLIC GUANIDINES

被引：30

作者：

PESCHKE, W

SCHIESSL, P

SCHMIDTCHEN, FP

BISSINGER, P

SCHIER, A

机构：

[1] TECH UNIV MUNICH, INST ORGAN CHEM & BIOCHEM, D-85747 GARCHING, GERMANY

[2] TECH UNIV MUNICH, INST ANORGAN CHEM, D-85747 GARCHING, GERMANY

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1995年 / 60卷 / 04期

关键词：

D O I：

10.1021/jo00109a041

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bicyclic guanidinium salts are versatile anchor groups for oxoanions. Their incorporation into modular artificial hosts calls for the reliable accessibility of chiral, regioselectively functionalized derivatives. Here the preparation of an ensemble 6-14 of suitable building blocks is described, which meets these requirements and may be introduced into polytopic receptors by various nucleophilic displacement reactions. The individual members of this class were conveniently prepared in satisfactory yield by functional group manipulation starting from the known differentially protected parent compound 4.

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页码：1039 / 1043

页数：5

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