ASTROCYTES CONVERT THE PARKINSONISM INDUCING NEUROTOXIN, MPTP, TO ITS ACTIVE METABOLITE, MPP+

被引：174

作者：

RANSOM, BR ^{[1
]}

KUNIS, DM ^{[1
]}

IRWIN, I ^{[1
]}

LANGSTON, JW ^{[1
]}

机构：

[1] INST MED RES,SAN JOSE,CA 95128

来源：

NEUROSCIENCE LETTERS | 1987年 / 75卷 / 03期

关键词：

D O I：

10.1016/0304-3940(87)90543-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

引用

页码：323 / 328

页数：6

共 17 条

[1]

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[8] SELECTIVE ACCUMULATION OF MPP+ IN THE SUBSTANTIA NIGRA - A KEY TO NEUROTOXICITY [J].

IRWIN, I ;

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LIFE SCIENCES, 1985, 36 (03) :207-212

[9] PARKINSONISM-INDUCING NEUROTOXIN, N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE - UPTAKE OF THE METABOLITE N-METHYL-4-PHENYLPYRIDINE BY DOPAMINE NEURONS EXPLAINS SELECTIVE TOXICITY [J].

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[10] PARGYLINE PREVENTS MPTP-INDUCED PARKINSONISM IN PRIMATES [J].

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