PALLADIUM CATALYZED [2+2+2]-CYCLOADDITION REACTIONS VIA CARBOPALLADATION OF 1,6-ENYNES

被引：50

作者：

BROWN, S

CLARKSON, S

GRIGG, R

SRIDHARAN, V

机构：

[1] UNIV LEEDS,SCH CHEM,LEEDS LS2 9JT,W YORKSHIRE,ENGLAND

[2] ICI PLC,FCMO,HUDDERSFIELD HD2 1FF,ENGLAND

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 01期

关键词：

D O I：

10.1016/S0040-4039(00)60082-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,6-Enynes react with aryl and heteroaryl halides via a [2+2+2]- process to furnish bicyclic products in moderate to good yields. In some cases the alkylpalladium(II) intermediate can be diverted to a [1+2]-process furnishing cyclopropanes or to a cyclohexene derivative. The cascade process is initiated by regiospecific carbopalladation of the enyne by the aryl- or heteroaryl-palladium (II) halide.

引用

页码：157 / 160

页数：4

共 10 条

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