HIGHLY EFFICIENT ENANTIOSELECTIVE PAUSON-KHAND REACTIONS

被引：90

作者：

HAY, AM ^{[1
]}

KERR, WJ ^{[1
]}

KIRK, GG ^{[1
]}

MIDDLEMISS, D ^{[1
]}

机构：

[1] UNIV STRATHCLYDE,DEPT PURE & APPL CHEM,GLASGOW G1 1XL,LANARK,SCOTLAND

来源：

ORGANOMETALLICS | 1995年 / 14卷 / 11期

关键词：

D O I：

10.1021/om00011a007

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Diastereomeric (alkyne)pentacarbonyldicobalt complexes containing the chiral phosphine ligand (R)-(+)-Glyphos have been synthesized and separated chromatographically. The isolated, optically pure diastereomeric complexes have been employed in intermolecular Pauson-Khand reactions, using anhydrous N-methylmorpholine N-oxide as the reaction promoter under mild conditions, to give high yields of cyclopentenone products in good to excellent enantiomeric excesses.

引用

页码：4986 / 4988

页数：3

共 31 条

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