SORGHUM-BICOLOR SHOOTS IN THE SYNTHESIS OF (S)-MANDELONITRILE

被引：19

作者：

KILJUNEN, E ^{[1
]}

KANERVA, LT ^{[1
]}

机构：

[1] UNIV TURKU,DEPT BIOMED,SF-20500 TURKU 50,FINLAND

来源：

TETRAHEDRON-ASYMMETRY | 1994年 / 5卷 / 03期

关键词：

D O I：

10.1016/S0957-4166(00)86193-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An inexpensive method for the preparation of (S)-mandelonitrile from benzaldehyde and HCN in diisopropyl ether with the chemical yield and enantiomeric excess of ca. 90 % is described. In this method, (S)-oxynitrilase in etiolated shoots of Sorghum bicolor is used as an asymmetric catalyst.

引用

收藏

页码：311 / 314

页数：4

相关论文

共 20 条

[1] RESOLUTION OF SECONDARY ALCOHOLS USING LIPASE IN DIISOPROPYL ETHER [J].

BEVINAKATTI, HS ;

BANERJI, AA ;

NEWADKAR, RV .

JOURNAL OF ORGANIC CHEMISTRY, 1989, 54 (10) :2453-2455

[2]

BOVE C, 1961, J BIOL CHEM, V236, P207

[3] SYNTHESIS OF OPTICALLY-ACTIVE SILYL PROTECTED CYANOHYDRINS [J].

BRUSSEE, J ;

LOOS, WT ;

KRUSE, CG ;

VANDERGEN, A .

TETRAHEDRON, 1990, 46 (03) :979-986

[4]

EFFENBERGER F, 1991, LIEBIGS ANN CHEM, P47

[5] ENZYME-CATALYZED REACTIONS .5. ENZYME-CATALYZED SYNTHESIS OF (S)-CYANOHYDRINS AND SUBSEQUENT HYDROLYSIS TO (S)-ALPHA-HYDROXY-CARBOXYLIC ACIDS [J].

EFFENBERGER, F ;

HORSCH, B ;

FORSTER, S ;

ZIEGLER, T .

TETRAHEDRON LETTERS, 1990, 31 (09) :1249-1252

[6] ENZYME-CATALYZED SYNTHESIS OF OPTICALLY-ACTIVE ALIPHATIC CYANOHYDRINS [J].

HUUHTANEN, TT ;

KANERVA, LT .

TETRAHEDRON-ASYMMETRY, 1992, 3 (10) :1223-1226

[7] ONE-POT SYNTHESIS OF OPTICALLY-ACTIVE CYANOHYDRIN ACETATES FROM ALDEHYDES VIA LIPASE-CATALYZED KINETIC RESOLUTION COUPLED WITH INSITU FORMATION AND RACEMIZATION OF CYANOHYDRINS [J].

INAGAKI, M ;

HIRATAKE, J ;

NISHIOKA, T ;

ODA, J .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (21) :5643-5649

[8]

JANSEN I, 1992, BIOTECHNOL APPL BIOC, V15, P90

[9] ENZYMATIC PREPARATION OF OPTICALLY-ACTIVE ALPHA-HYDROXY AND BETA-HYDROXY CARBOXYLIC-ACID DERIVATIVES [J].

KANERVA, LT ;

SUNDHOLM, O .

ACTA CHEMICA SCANDINAVICA, 1993, 47 (08) :823-825

[10] ENZYMATIC RESOLUTION OF OPTICALLY-ACTIVE ALIPHATIC CYANOHYDRINS [J].

KANERVA, LT ;

KILJUNEN, E ;

HUUHTANEN, TT .

TETRAHEDRON-ASYMMETRY, 1993, 4 (11) :2355-2361