ENZYMATIC SELECTIVE TRANSFORMATIONS OF DIETHYL FUMARATE

被引：10

作者：

QUIROS, M ^{[1
]}

ASTORGA, C ^{[1
]}

REBOLLEDO, F ^{[1
]}

GOTOR, V ^{[1
]}

机构：

[1] UNIV OVIEDO,DEPT QUIM ORGAN & INORGAN,E-33071 OVIEDO,SPAIN

来源：

TETRAHEDRON | 1995年 / 51卷 / 28期

关键词：

D O I：

10.1016/0040-4020(95)00391-K

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Candida antarctica lipase selectively catalyses transformations of diethyl fumarate in organic solvents. A range of nitrogen nucleophiles, including ammonia, can be succesfully used in these enzymatic reactions, monoamides and monohydrazides being obtained in high to moderate yields. In contrast, diethyl maleate is nor an adequate substrate for this enzyme.

引用

页码：7715 / 7720

页数：6

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