STUDIES ON THE MECHANISM OF MPTP OXIDATION BY HUMAN-LIVER MONOAMINE OXIDASE-B

被引：7

作者：

GESSNER, W ^{[1
]}

BROSSI, A ^{[1
]}

BEMBENEK, ME ^{[1
]}

FRITZ, RR ^{[1
]}

ABELL, CW ^{[1
]}

机构：

[1] UNIV TEXAS,MED BRANCH,DEPT HUMAN BIOL CHEM & GENET,DIV BIOCHEM,GALVESTON,TX 77550

来源：

FEBS LETTERS | 1986年 / 199卷 / 01期

关键词：

D O I：

10.1016/0014-5793(86)81232-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：100 / 102

页数：3

共 17 条

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LIFE SCIENCES, 1985, 36 (11) :1125-1134

[2] POTENTIAL BIOACTIVATION PATHWAYS FOR THE NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) [J].

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[3] METABOLISM OF THE NEUROTOXIC TERTIARY AMINE, MPTP, BY BRAIN MONOAMINE-OXIDASE [J].

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CASTAGNOLI, N .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 120 (02) :574-578

[4] CONVERSION OF THE NEUROTOXIC PRECURSOR 1-METHYL-4-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE INTO ITS PYRIDINIUM METABOLITE BY HUMAN-PLATELET MONOAMINE-OXIDASE TYPE-B [J].

DAPRADA, M ;

CESURA, AM ;

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[5]

DENNEY RM, 1983, MOL PHARMACOL, V24, P60

[6] HUMAN-LIVER MAO-A AND MAO-B SEPARATED BY IMMUNOAFFINITY CHROMATOGRAPHY WITH MAO-B-SPECIFIC MONOCLONAL-ANTIBODY [J].

DENNEY, RM ;

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PATEL, NT ;

ABELL, CW .

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[7] METABOLISM OF THE NEUROTOXIN IN MPTP BY HUMAN-LIVER MONOAMINE OXIDASE-B [J].

FRITZ, RR ;

ABELL, CW ;

PATEL, NT ;

GESSNER, W ;

BROSSI, A .

FEBS LETTERS, 1985, 186 (02) :224-228

[8] CONVERSION OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) AND ITS 5-METHYL ANALOG INTO PYRIDINIUM SALTS [J].

GESSNER, W ;

BROSSI, A ;

SHEN, RS ;

FRITZ, RR ;

ABELL, CW .

HELVETICA CHIMICA ACTA, 1984, 67 (08) :2037-2042

[9] REDUCTION OF PHENYL-SUBSTITUTED PYRIDINIUM METHOIODIDES WITH SODIUM-BOROHYDRIDE - FORMATION OF AMINE-BORANE COMPLEXES IN WATER [J].

GESSNER, W ;

BROSSI, A .

SYNTHETIC COMMUNICATIONS, 1985, 15 (10) :911-916

[10]

HEIKKILA RE, 1984, NATURE, V311, P467, DOI 10.1038/311467a0

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