DETECTION OF CLENBUTEROL RESIDUES IN HAIR

被引：35

作者：

ADAM, A

GERVAIS, N

PANOYAN, A

ONG, H

BELIVEAU, L

AYOTTE, C

DELAHAUT, P

机构：

[1] UNIV MONTREAL,DEPT EDUC PHYS,MONTREAL,PQ H3C 3J7,CANADA

[2] INST NATL RECH SCI SANTE,POINTE CLAIRE,PQ H9R 1G6,CANADA

[3] CER,HORMONOL LAB,B-6900 MARLOIE,BELGIUM

来源：

ANALYST | 1994年 / 119卷 / 12期

关键词：

CLENBUTEROL; BETA(2)-AGONIST RESIDUE; ENZYME IMMUNOASSAY; HAIR ANALYSIS;

D O I：

10.1039/an9941902663

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Sixty rats were grown in the presence of 10 (n = 30) and 100 (n = 30) pg kg(-1) body mass of clenbuterol for a period of 10 d, An immunoextraction step coupled with a competitive enzyme immunoassay allowed the quantification of clenbuterol in hair upon 20 (10 mu g kg(-1)) and 30 d (100 mu g kg(-1)) after the last dose. This accumulation in hair contrasts with the rapid clearance in tissues. The nature of the immunoreactive material was confirmed by mass spectrometry.

引用

页码：2663 / 2666

页数：4

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