SYNTHESIS AND SELECTIVE RADICAL CLEAVAGE OF C-4'-MODIFIED OLIGONUCLEOTIDES

被引：35

作者：

GIESE, B

DUSSY, A

ELIE, C

ERDMANN, P

SCHWITTER, U

机构：

[1] Departement Chemie der Universität, Basel, CH-4056

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1994年 / 33卷 / 18期

关键词：

D O I：

10.1002/anie.199418611

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fragments 3 and 4 are formed selectively upon irradiation of 2 in aqueous solution. This proves that sites of DNA strand scission can be designated by incorporation of 1 in oligonucleotides. (Figure Presented.) Copyright © 1994 by VCH Verlagsgesellschaft mbH, Germany

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页码：1861 / 1863

页数：3

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