APPLICATIONS OF CELLULOSE-BASED CHIRAL STATIONARY PHASES IN RESOLUTION OF DRUG RACEMATES - A MINI REVIEW

被引：10

作者：

ABOULENEIN, HY

机构：

来源：

ANALYTICAL LETTERS | 1992年 / 25卷 / 02期

关键词：

CELLULOSE CHIRAL STATIONARY PHASES; APPLICATION; RESOLUTION OF DRUG RACEMATES; ENANTIOMERIC SEPARATION;

D O I：

10.1080/00032719208018522

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An overview of various cellulose-based chiral stationary phases (CSP's) which are commercially available for direct separation of drug racemates to their corresponding enantiomers is presented. The advantages, disadvantages, and mechanisms of resolution of these CSP's are briefly discussed. Examples of baseline resolution of some drug racemates are presented and the number of successful resolutions on these CSP's is increasing rapidly.

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页码：231 / 238

页数：8

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