IRREVERSIBLE ENZYME INHIBITORS .112. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF DIHYDROFOLIC REDUCTASE DERIVED FROM 4,6-DIAMINO-1,2-DIHYDRO-2,2-DIMETHYL-1-PHENYL-S-TRIAZINE SUBSTITUTED WITH A TERMINAL SULFONYL FLUORIDE .2.

被引：12

作者：

BAKER, BR

LOURENS, GJ

机构：

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1968年 / 11卷 / 01期

关键词：

D O I：

10.1021/jm00307a007

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：38 / &

共 11 条

[1] NON-CLASSICAL ANTIMETABOLITES .6. 4-(IODOACETAMIDO)-SALICYLIC ACID, AN EXO-ALKYLATING IRREVERSIBLE INHIBITOR [J].

BAKER, BR ;

LEE, WW ;

TONG, E .

JOURNAL OF THEORETICAL BIOLOGY, 1962, 3 (03) :459-&

[2] IRREVERSIBLE ENZYME INHIBITORS .105. DIFFERENTIAL IRREVERSIBLE INHIBITION OF VERTEBRATE DIHYDROFOLIC REDUCTASES BY DERIVATIVES OF 4,6-DIAMINO-1,2-DIHYDRO-2,2-DIMETHYL-1-PHENYL-S-TRIAZINES SUBSTITUTED WITH A TERMINAL SULFONYL FLUORIDE [J].

BAKER, BR ;

LOURENS, GJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (06) :1113-+

[3] IRREVERSIBLE ENZYME INHIBITORS .109. CANDIDATE IRREVERSIBLE INHIBITORS OF DIHYDROFOLIC REDUCTASE DERIVED FROM 4,6-DIAMINO-1,2-DIHYDRO-2,2-DIMETHYL-1-PHENYL-S-TRIAZINE .3. [J].

BAKER, BR ;

LOURENS, GJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (01) :26-&

[4]

BAKER BR, 1966, J PHARM SCI, V55, P295

[5] ANALOGS OF TETRAHYDROFOLOC ACID 34 - HYDROPHOBIC BONDING TO DIHYDROFOLOC REDUCTASE .6. MODE OF PHENYL BINDING OF SOME 6-ARYLPYRIMIDINES [J].

BAKER, BR ;

SHAPIRO, HS .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1966, 55 (03) :308-&

[6] ANALOGS OF TETRAHYDROFOLIC ACID .35. HYDROPHOBIC BONDING TO DIHYDROFOLIC REDUCTASE .7. SPECIES DIFFERENCES WITH SUBSTITUTED 4,6-DIAMINO-1,2-DIHYDRO-S-TRIAZINES [J].

BAKER, BR ;

HO, BT .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1966, 55 (05) :470-&

[7]

BAKER BR, 1967, DESIGN ACTIVESITEDIR, pCH10

[8]

BAKER BR, 1967, DESIGN ACTIVESITEDIR, pCH9

[9]

BAKER BR, IN PRESS

[10]

BAKER BR, 1967, DESIGN ACTIVESITEDIR, pCH8

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