CONJUGATE ADDITION OF CHLORIDE TO ALPHA,BETA-UNSATURATED CHIRAL IMIDES PROMOTED BY BCL3-DERIVATIVES - A SYNTHESIS OF 3-CHLOROBUTANOIC ACID

被引：10

作者：

CARDILLO, G ^{[1
]}

DESIMONE, A ^{[1
]}

GENTILUCCI, L ^{[1
]}

TOMASINI, C ^{[1
]}

机构：

[1] UNIV BOLOGNA,CSFM,I-40126 BOLOGNA,ITALY

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 06期

关键词：

D O I：

10.1039/c39940000735

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The conjugate addition of chloride to chiral but-2-enoic imides promoted by BCl3-derivatives proceeds with diastereoisomeric ratios of up to 90 : 10 and affords the corresponding 3-chlorobutanoic imides from which, after mild hydrolysis, the 3-chlorobutanoic acid is obtained.

引用

收藏

页码：735 / 763

页数：29

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