MicroRNA Targets - How to predict?

被引：6

作者：

Das, Nabajit ^{[1
]}

机构：

[1] KIIT Univ, Sch Biotechnol, Bhubaneswar 751024, Odisha, India

来源：

BIOINFORMATION | 2012年 / 8卷 / 18期

关键词：

pre-miRNA; miRNA; biogenesis; algorithms; in-silico biology;

D O I：

10.6026/97320630008841

中图分类号：

Q [生物科学];

学科分类号：

07 [理学]; 0710 [生物学]; 09 [农学];

摘要：

A number of web tools are available for the prediction and identification of target microRNAs (miRNAs). The choice, availability, validity and selection of an optimal yet appropriate tool are a challenge for the design of high throughput assays with promising miRNA targets. The current trends and challenges for target microRNAs (miRNAs) prediction, identification and selection is described in this review.

引用

页码：841 / 845

页数：5

共 31 条

[1]

Clustering and conservation patterns of human microRNAs [J].

Altuvia, Y ;

Landgraf, P ;

Lithwick, G ;

Elefant, N ;

Pfeffer, S ;

Aravin, A ;

Brownstein, MJ ;

Tuschl, T ;

Margalit, H .

NUCLEIC ACIDS RESEARCH, 2005, 33 (08) :2697-2706

[2]

A uniform system for microRNA annotation [J].

Ambros, V ;

Bartel, B ;

Bartel, DP ;

Burge, CB ;

Carrington, JC ;

Chen, XM ;

Dreyfuss, G ;

Eddy, SR ;

Griffiths-Jones, S ;

Marshall, M ;

Matzke, M ;

Ruvkun, G ;

Tuschl, T .

RNA, 2003, 9 (03) :277-279

[3]

Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes [J].

Baskerville, S ;

Bartel, DP .

RNA, 2005, 11 (03) :241-247

[4]

Mammalian mirtron genes [J].

Berezikov, Eugene ;

Chung, Wei-Jen ;

Willis, Jason ;

Cuppen, Edwin ;

Lai, Eric C. .

MOLECULAR CELL, 2007, 28 (02) :328-336

[5]

Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs [J].

Bohnsack, MT ;

Czaplinski, K ;

Görlich, D .

RNA, 2004, 10 (02) :185-191

[6]

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs [J].

Cai, XZ ;

Hagedorn, CH ;

Cullen, BR .

RNA, 2004, 10 (12) :1957-1966

[7]

Das N, 2012, BIOMIRROR, V3

[8]

MicroRNA biogenesis: there's more than one way to skin a cat [J].

Faller, Michael ;

Guo, Feng .

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, 2008, 1779 (11) :663-667

[9]

Gregory Richard I., 2006, V342, P33, DOI 10.1385/1-59745-123-1:33

[10]

miRBase: microRNA sequences, targets and gene nomenclature [J].

Griffiths-Jones, Sam ;

Grocock, Russell J. ;

van Dongen, Stijn ;

Bateman, Alex ;

Enright, Anton J. .

NUCLEIC ACIDS RESEARCH, 2006, 34 :D140-D144

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