学术探索
学术期刊
新闻热点
数据分析
智能评审

TRANSMISSION-BLOCKING IMMUNITY AGAINST MALARIA AND OTHER VECTOR-BORNE DISEASES

被引：88
作者：
KASLOW, DC
机构：
[1] National Institutes of Health, Bethesda
来源：
CURRENT OPINION IN IMMUNOLOGY | 1993年 / 5卷 / 04期
关键词：
D O I：
10.1016/0952-7915(93)90037-S
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Antibodies to sexual stage malaria parasites block transmission of Plasmodium by female mosquitoes. With the recent isolation of genes encoding several of the target antigens of transmission-blocking antibodies, the development of a subunit transmission-blocking vaccine against malaria is now a realistic goal.
引用
收藏
页码：557 / 565
页数：9
相关论文
共 54 条
[1]   A STAGE SPECIFIC GENE EXPRESSED AT THE ONSET OF GAMETOCYTOGENESIS IN PLASMODIUM-FALCIPARUM [J].
ALANO, P ;
PREMAWANSA, S ;
BRUCE, MC ;
CARTER, R .
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1991, 46 (01) :81-88
[2]   RECOMBINANT PFS25 PROTEIN OF PLASMODIUM-FALCIPARUM ELICITS MALARIA TRANSMISSION-BLOCKING IMMUNITY IN EXPERIMENTAL-ANIMALS [J].
BARR, PJ ;
GREEN, KM ;
GIBSON, HL ;
BATHURST, IC ;
QUAKYI, IA ;
KASLOW, DC .
JOURNAL OF EXPERIMENTAL MEDICINE, 1991, 174 (05) :1203-1208
[3]   PLASMODIUM-FALCIPARUM - AN ABUNDANT STAGE-SPECIFIC PROTEIN EXPRESSED DURING EARLY GAMETOCYTE DEVELOPMENT [J].
CARTER, R ;
GRAVES, PM ;
CREASEY, A ;
BYRNE, K ;
READ, D ;
ALANO, P ;
FENTON, B .
EXPERIMENTAL PARASITOLOGY, 1989, 69 (02) :140-149
[4]   PROPERTIES OF EPITOPES OF PFS 48/45, A TARGET OF TRANSMISSION BLOCKING MONOCLONAL-ANTIBODIES, ON GAMETES OF DIFFERENT ISOLATES OF PLASMODIUM-FALCIPARUM [J].
CARTER, R ;
GRAVES, PM ;
KEISTER, DB ;
QUAKYI, IA .
PARASITE IMMUNOLOGY, 1990, 12 (06) :587-603
[5]   RESTRICTED OR ABSENT IMMUNE-RESPONSES IN HUMAN-POPULATIONS TO PLASMODIUM-FALCIPARUM GAMETE ANTIGENS THAT ARE TARGETS OF MALARIA TRANSMISSION-BLOCKING ANTIBODIES [J].
CARTER, R ;
GRAVES, PM ;
QUAKYI, IA ;
GOOD, MF .
JOURNAL OF EXPERIMENTAL MEDICINE, 1989, 169 (01) :135-147
[6]   MALARIA VACCINES - PROGRESS AND PROBLEMS [J].
COX, FEG .
TRENDS IN BIOTECHNOLOGY, 1991, 9 (11) :389-393
[7]   PGS28 BELONGS TO A FAMILY OF EPIDERMAL GROWTH-FACTOR LIKE ANTIGENS THAT ARE TARGETS OF MALARIA TRANSMISSION-BLOCKING ANTIBODIES [J].
DUFFY, PE ;
PIMENTA, P ;
KASLOW, DC .
JOURNAL OF EXPERIMENTAL MEDICINE, 1993, 177 (02) :505-510
[8]   PFS2400 CAN MEDIATE ANTIBODY-DEPENDENT MALARIA TRANSMISSION INHIBITION AND MAY BE THE PLASMODIUM-FALCIPARUM 11.1 GENE-PRODUCT [J].
FENG, Z ;
HOFFMANN, RN ;
NUSSENZWEIG, RS ;
TSUJI, M ;
FUJIOKA, H ;
AIKAWA, M ;
LENSEN, THW ;
PONNUDURAI, T ;
POLOGE, LG .
JOURNAL OF EXPERIMENTAL MEDICINE, 1993, 177 (02) :273-281
[9]   CONSERVED AND VARIANT EPITOPES OF TARGET ANTIGENS OF TRANSMISSION-BLOCKING ANTIBODIES AMONG ISOLATES OF PLASMODIUM-FALCIPARUM FROM MALAYSIA [J].
FOO, A ;
CARTER, R ;
LAMBROS, C ;
GRAVES, P ;
QUAKYI, I ;
TARGETT, GAT ;
PONNUDURAI, T ;
LEWIS, GE .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1991, 44 (06) :623-631
[10]   BIOSYNTHESIS OF THE 25-KDA PROTEIN IN THE MACROGAMETES ZYGOTES OF PLASMODIUM-FALCIPARUM [J].
FRIES, HCW ;
LAMERS, MBAC ;
VANDEURSEN, J ;
PONNUDURAI, T ;
MEUWISSEN, JHET .
EXPERIMENTAL PARASITOLOGY, 1990, 71 (02) :229-235
123456