雌马酚产生细菌及其雌马酚合成代谢机制

被引:8
作者
胡云霏
陈华海
尹业师
机构
[1] 湘南优势植物资源综合利用湖南省重点实验室湖南科技学院化学与生物工程学院
基金
湖南省自然科学基金;
关键词
雌马酚; 肠道细菌; 大豆苷元; 染料木素; 代谢机制;
D O I
10.13343/j.cnki.wsxb.20180451
中图分类号
Q939.9 [应用微生物学];
学科分类号
071005 [微生物学];
摘要
大豆食品中通常富含染料木素和大豆苷元等异黄酮素,人和动物肠道中的某些细菌具有将异黄酮素代谢转化为S-雌马酚的能力。到目前为止,S-雌马酚被认为是一种具有潜在健康调节作用的化合物。啮齿类动物均具备产雌马酚的能力,但不同人群之间存在差异,产雌马酚细菌是否存在可能是造成这种差异的重要原因;不同产雌马酚细菌的代谢机制可能不同,并影响机体最终产雌马酚的能力。本文对已知的各种产雌马酚细菌及其细菌的雌马酚合成机制进行综述,以期为进一步了解雌马酚产生个体差异、雌马酚代谢转化效率、体外雌马酚的发酵生产,以及临床产雌马酚细菌的应用等提供理论参考。
引用
收藏
页码:1452 / 1462
页数:11
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