Annulative tandem reactions based on Pd0/tBu3P-catalyzed cross-coupling and C(sp3)-H bond activation

被引：119

作者：

Dong, CG

Hu, QS ^{[1
]}

机构：

[1] CUNY Coll Staten Isl, Dept Chem, Staten Isl, NY 10314 USA

[2] CUNY, Grad Ctr, Staten Isl, NY 10314 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 14期

关键词：

C-H activation; cross-coupling; palladium phosphanes; tandem reactions;

D O I：

10.1002/anie.200504310

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) All together now: Pd0/tBu 3P-catalyzed annulative tandem reactions of 1,2-dihalobenzenes were carried out with hindered Grignard reagents. This new type of tandem reaction is believed to occur through cross-coupling followed by cyclization with C(sp 3)-H bond activation as the key step and allows one-step access to potentially useful substituted fluorenes in high yield from readily available 1,2-dibromobenzenes and 1-bromo-2-iodobenzene. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2289 / 2292

页数：4

共 63 条

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