Anti-IL-17 Receptor Antibody AMG 827 Leads to Rapid Clinical Response in Subjects with Moderate to Severe Psoriasis: Results from a Phase I, Randomized, Placebo-Controlled Trial

被引:122
作者
Papp, Kim A. [1 ]
Reid, Cathy [2 ]
Foley, Peter [3 ,4 ,5 ]
Sinclair, Rod [3 ,4 ,5 ]
Salinger, David H. [6 ]
Williams, Gary [7 ]
Dong, Hua [8 ]
Krueger, James G. [9 ]
Russell, Chris B. [10 ]
Martin, David A. [10 ]
机构
[1] Prob Med Res, Waterloo, ON, Canada
[2] Royal Adelaide Hosp, Dermatol Unit, Adelaide, SA 5000, Australia
[3] Univ Melbourne, St Vincents Hosp Melbourne, Dept Med Dermatol, Melbourne, Vic, Australia
[4] Univ Melbourne, St Vincents Hosp Melbourne, Dept Dermatol, Melbourne, Vic, Australia
[5] Skin & Canc Fdn, Carlton, Vic, Australia
[6] Amgen Inc, Pharmacokinet & Drug Metab, Seattle, WA USA
[7] Amgen Inc, Early Dev, Thousand Oaks, CA USA
[8] Amgen Inc, Biostat, San Francisco, CA USA
[9] Rockefeller Univ, New York, NY 10021 USA
[10] Amgen Inc, Med Sci, Seattle, WA USA
关键词
FAMILY;
D O I
10.1038/jid.2012.163
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100227 [皮肤病学];
摘要
引用
收藏
页码:2466 / 2469
页数:4
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