Synthesis of Aryl Sulfonamides via Palladium-Catalyzed Chlorosulfonylation of Arylboronic Acids

被引：95

作者：

DeBergh, J. Robb ^{[1
]}

Niljianskul, Nootaree ^{[1
]}

Buchwald, Stephen L. ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2013年 / 135卷 / 29期

基金：

美国国家卫生研究院;

关键词：

MIYAURA COUPLING REACTIONS; CHLORINE BOND SCISSION; ONE-POT SYNTHESIS; CROSS-COUPLINGS; SULFONYL CHLORIDES; HETEROARYL SULFONAMIDES; SULFUR-COMPOUNDS; METHANOLYSIS; DISCOVERY; THIOLS;

D O I：

10.1021/ja405949a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A palladium-catalyzed method for the preparation of sulfonamides is described. The process exhibits significant functional group tolerance and allows for the preparation of a number of arylsulfonyl chlorides and sulfonamides under mild conditions.

引用

收藏

页码：10638 / 10641

页数：4

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