High diversity of HIV type 1 in Algeria

被引：15

作者：

Bouzeghoub, S

Jauvin, V

Recordon-Pinson, P

Garrigue, I

Amrane, A

Belabbes, EH

Fleury, HJ ^{[1
]}

机构：

[1] Univ Bordeaux 2, UPRES EA 2968, Virol Lab, Grp Hosp Pellegrin, F-33076 Bordeaux, France

[2] Inst Pasteur, Lab Natl Reference VIH SIDA, Algiers, Algeria

[3] Hop El Hadi Flici, Serv Malad Infect, Algiers, Algeria

来源：

AIDS RESEARCH AND HUMAN RETROVIRUSES | 2006年 / 22卷 / 04期

关键词：

D O I：

10.1089/aid.2006.22.367

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We have sequenced different genes of HIV-1 strains from infected individuals recruited in various geographic parts of Algeria; phylogenetic trees were constructed yielding molecular characterization of these strains. Subtype B accounts for 56% of the samples studied and is therefore the predominant subtype, particularly in the north part of the country; but there is a high diversity of the virus including CRF02_AG, CRF06_cpx, CRF02/CRF06 interrecombinants, and different other intersubtype and/or inter-CRF recombinants. The prevalence of these non-B viruses increases in the south part of Algeria that borders sub-Saharan African countries. The high diversity of HIV-1 in Algeria has implications for virological follow-up, resistance surveys, and vaccine

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页码：367 / 372

页数：6

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