Palladium-catalyzed H-D exchange reaction under hydrothermal condition

被引:45
作者
Matsubara, S [1 ]
Yokota, Y [1 ]
Oshima, K [1 ]
机构
[1] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Nishikyo Ku, Kyoto 6158510, Japan
关键词
D O I
10.1246/cl.2004.294
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Alkenes and alkanes were converted into fully deuterium labelled ones by treatment with palladium on charcoal and deuterium oxide under hydrothermal condition. The simple method to get fully deuterium labelled compounds is easy to apply to various types of organic compounds.
引用
收藏
页码:294 / 295
页数:2
相关论文
共 22 条
[1]   Roles of water for chemical reactions in high-temperature water [J].
Akiya, N ;
Savage, PE .
CHEMICAL REVIEWS, 2002, 102 (08) :2725-2750
[2]   NUCLEAR MAGNETIC RESONANCE SPECTRA AND CONFORMATIONS OF DEUTERATED CYCLOOCTANES [J].
ANET, FAL ;
STJACQUE.M .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1966, 88 (11) :2585-&
[3]   A SIMPLIFIED PREPARATION OF FULLY DEUTERATED HIGH MOLECULAR WEIGHT HYDROCARBONS [J].
ATKINSON, JG ;
LUKE, MO ;
STUART, RS .
CANADIAN JOURNAL OF CHEMISTRY, 1967, 45 (13) :1511-&
[4]   Microwave-enhanced metal- and acid-catalysed hydrogen isotope exchange reactions [J].
Barthez, JM ;
Filikov, AV ;
Frederiksen, LB ;
Huguet, ML ;
Jones, JR ;
Lu, SY .
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1998, 76 (06) :726-728
[5]  
Bröll D, 1999, ANGEW CHEM INT EDIT, V38, P2999
[6]   The activation barrier to axial torsion in 2,2'-bis(diphenylphosphino)biphenyl [J].
Desponds, O ;
Schlosser, M .
TETRAHEDRON LETTERS, 1996, 37 (01) :47-48
[7]   Microwave-assisted deuterium exchange reactions for the preparation of reactive intermediates [J].
Fodor-Csorba, K ;
Galli, G ;
Holly, S ;
Gäcs-Baitz, E .
TETRAHEDRON LETTERS, 2002, 43 (21) :3789-3792
[8]  
GANETT JL, 1967, J AM CHEM SOC, V89, P4545
[9]   Heck reactions in hydrothermal, sub-critical water: water density as an important reaction variable [J].
Gron, LU ;
LaCroix, JE ;
Higgins, CJ ;
Steelman, KL ;
Tinsley, AS .
TETRAHEDRON LETTERS, 2001, 42 (49) :8555-8557
[10]   Microwave-enhanced aromatic dehalogenation studies: a rapid deuterium-labelling procedure [J].
Jones, JR ;
Lockley, WJS ;
Lu, SY ;
Thompson, SP .
TETRAHEDRON LETTERS, 2001, 42 (02) :331-332