Graphene: Promises, Facts, Opportunities, and Challenges in Nanomedicine

被引:606
作者
Mao, Hong Ying [1 ]
Laurent, Sophie [2 ]
Chen, Wei [1 ,3 ]
Akhavan, Omid [4 ,5 ]
Imani, Mohammad [6 ]
Ashkarran, Ali Akbar [7 ]
Mahmoudi, Morteza [8 ,9 ]
机构
[1] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore
[2] Univ Mons, Dept Gen Organ & Biomed Chem, NMR & Mol Imaging Lab, B-7000 Mons, Belgium
[3] Natl Univ Singapore, Dept Phys, Singapore 117542, Singapore
[4] Sharif Univ Technol, Dept Phys, Tehran, Iran
[5] Sharif Univ Technol, Inst Nanosci & Nanotechnol, Tehran, Iran
[6] Iran Polymer & Petrochem Inst, Novel Drug Delivery Syst Dept, Tehran, Iran
[7] Univ Mazandaran, Fac Basic Sci, Dept Phys, Babolsar, Iran
[8] Univ Tehran Med Sci, Nanotechnol Res Ctr, Fac Pharm, Tehran, Iran
[9] Univ Tehran Med Sci, Dept Nanotechnol, Fac Pharm, Tehran, Iran
关键词
HIGH-QUALITY GRAPHENE; PROTEIN-NANOPARTICLE INTERACTIONS; DIRECT ELECTROCHEMISTRY; BALLISTIC TRANSPORT; CARBON NANOTUBES; FACILE SYNTHESIS; GRAPHITE OXIDE; IN-VITRO; PHOTOCATALYTIC REDUCTION; PHOTOTHERMAL THERAPY;
D O I
10.1021/cr300335p
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Graphene, a two-dimensional (2D) sheet of sp2-hybridized carbon atoms packed into a honeycomb lattice, has led to an explosion of interest in the field of materials science, physics, chemistry, and biotechnology since the few-layers graphene (FLG) flakes were isolated from graphite in 2004. For an extended search, derivatives of nanomedicine such as biosensing, biomedical, antibacterial, diagnosis, cancer and photothermal therapy, drug delivery, stem cell, tissue engineering, imaging, protein interaction, DNA, RNA, toxicity, and so on were also added. Since carbon nanotubes are normally described as rolled-up cylinders of graphene sheets and the controllable synthesis of nanotubes is well developed, longitudinally unzipping carbon nanotubes represents a novel strategy to obtain graphene nanoribbons (GNRs) of precise dimensions.
引用
收藏
页码:3407 / 3424
页数:18
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