The UCSC Cancer Genomics Browser: update 2013

被引：131

作者：

Goldman, Mary ^{[1
]}

Craft, Brian ^{[1
]}

Swatloski, Teresa ^{[1
]}

Ellrott, Kyle ^{[1
]}

Cline, Melissa ^{[1
]}

Diekhans, Mark ^{[1
]}

Ma, Singer ^{[1
]}

Wilks, Chris ^{[1
]}

Stuart, Josh ^{[1
]}

Haussler, David ^{[2
]}

Zhu, Jingchun ^{[1
]}

机构：

[1] Univ Calif Santa Cruz, Ctr Biomol Sci & Engn, Santa Cruz, CA 95064 USA

[2] Univ Calif Santa Cruz, Howard Hughes Med Inst, Santa Cruz, CA 95064 USA

来源：

NUCLEIC ACIDS RESEARCH | 2013年 / 41卷 / D1期

基金：

美国国家科学基金会;

关键词：

DNA METHYLATION; GENES;

D O I：

10.1093/nar/gks1008

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The UCSC Cancer Genomics Browser (https://genome-cancer.ucsc.edu/) is a set of web-based tools to display, investigate and analyse cancer genomics data and its associated clinical information. The browser provides whole-genome to base-pair level views of several different types of genomics data, including some next-generation sequencing platforms. The ability to view multiple datasets together allows users to make comparisons across different data and cancer types. Biological pathways, collections of genes, genomic or clinical information can be used to sort, aggregate and zoom into a group of samples. We currently display an expanding set of data from various sources, including 201 datasets from 22 TCGA (The Cancer Genome Atlas) cancers as well as data from Cancer Cell Line Encyclopedia and Stand Up To Cancer. New features include a completely redesigned user interface with an interactive tutorial and updated documentation. We have also added data downloads, additional clinical heatmap features, and an updated Tumor Image Browser based on Google Maps. New security features allow authenticated users access to private datasets hosted by several different consortia through the public website.

引用

页码：D949 / D954

页数：6

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