Functionalised cyclopentadienyl zirconium compounds as potential anticancer drugs

被引：20

作者：

Allen, Olivia R. ^{[1
]}

Knox, Richard J. ^{[2
]}

McGowan, Patrick C. ^{[1
]}

机构：

[1] Univ Leeds, Dept Chem, Leeds LS2 9JT, W Yorkshire, England

[2] Morvus Technol Ltd, Ty Myddfai, Carmarthen SA32 8HZ, Dyfed, Wales

来源：

DALTON TRANSACTIONS | 2008年 / 39期

关键词：

D O I：

10.1039/b812244j

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

New neutral and ionic functionalised zirconocene dichloride compounds have been isolated and characterised. The ionic zirconocene exhibits excellent cytotoxicity against a range of human tumour cell lines, which represents the first active anticancer zirconocene dichloride compound.

引用

页码：1293 / 1295

页数：3

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