Open-air oxidative Heck reactions at room temperature

被引:70
作者
Enquist, PA [1 ]
Lindh, J [1 ]
Nilsson, P [1 ]
Larhed, M [1 ]
机构
[1] BMC, Dept Med Chem, Uppsala, Sweden
关键词
D O I
10.1039/b517152k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Palladium(II)-catalyzed oxidative Heck arylation reactions proceed at room temperature with atmospheric air as the sole reoxidant. Using arylboronic acids as arylating agents and inexpensive 2,9-dimethyl-1,10-phenanthroline as the supporting ligand, efficient vinylic substitution reactions were obtained both with electron-poor and electron-rich olefins on a 1 - 50 mmol scale.
引用
收藏
页码:338 / 343
页数:6
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