Well-controlled synthesis of boronic-acid functionalised poly(lactide)s: a versatile platform for biocompatible polymer conjugates and sensors

被引:13
作者
Cross, Alison J. [1 ]
Davidson, Matthew G. [1 ]
Garcia-Vivo, Daniel [1 ]
James, Tony D. [1 ]
机构
[1] Univ Bath, Dept Chem, Ctr Sustainable Chem Technol, Bath BA2 7AY, Avon, England
关键词
RING-OPENING POLYMERIZATION; CROSS-COUPLING REACTIONS; NANOPARTICLES; FORMULATION; LACTIDE; FLUORESCENCE; COMPLEXES;
D O I
10.1039/c2ra20373a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report the controlled synthesis of boronic-acid terminated polylactides via the use of a protected boronic acid-functionalised ring-opening polymerisation initiator and the subsequent deprotection of the resultant polymer. We have demonstrated the utility of this approach to biocompatible polymer conjugates of biologically-relevant diols using an indicator-displacement assay.
引用
收藏
页码:5954 / 5956
页数:3
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