Secondary product formation in plant tissue cultures

被引:113
作者
Collin, HA [1 ]
机构
[1] Univ Liverpool, Sch Biol Sci, Liverpool L69 3BX, Merseyside, England
关键词
plant secondary products; tissue culture; cell suspension culture; biomass; enzyme immobilisation;
D O I
10.1023/A:1013374417961
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The formation of secondary products in plant tissue cultures is reviewed. The conditions for the enhanced production of secondary products, which include alkaloids, terpenoids, steroids and phenolics, can be regulated in a number of ways. For example, manipulation of secondary product formation is possible by varying the nutrient composition of the growth medium, light, temperature and pH, and by the use of elicitors, permeabilisation and two-stage systems. Molecular engineering and the use of biomass and large-scale culture are described along with future prospects for the commercial production of secondary products from cell suspension cultures.
引用
收藏
页码:119 / 134
页数:16
相关论文
共 51 条
[21]   Plant cell culture combined with chemistry - A powerful route to complex natural products [J].
Kutney, JP .
PURE AND APPLIED CHEMISTRY, 1996, 68 (11) :2073-2080
[22]   Expression of two consecutive genes of a secondary metabolic pathway in transgenic tobacco: molecular diversity influences levels of expression and product accumulation [J].
Leech, MJ ;
May, K ;
Hallard, D ;
Verpoorte, R ;
De Luca, V ;
Christou, P .
PLANT MOLECULAR BIOLOGY, 1998, 38 (05) :765-774
[23]  
LIEBMANN J, 1994, CANCER CHEMOTH PHARM, V33, P331
[24]  
LOWE KC, 1996, PLANT TISSUE CULTURE, V2, P175
[25]   HIGH-YIELD FORMATION OF ARBUTIN FROM HYDROQUINONE BY CELL-SUSPENSION CULTURES OF RAUWOLFIA-SERPENTINA [J].
LUTTERBACH, R ;
STOCKIGT, J .
HELVETICA CHIMICA ACTA, 1992, 75 (06) :2009-2011
[26]   THE IN-VITRO PRODUCTION OF AN ANTHOCYANIN FROM CALLUS-CULTURES OF OXALIS-LINEARIS [J].
MEYER, HJ ;
VANSTADEN, J .
PLANT CELL TISSUE AND ORGAN CULTURE, 1995, 40 (01) :55-58
[27]   Rosmarinic acid and related phenolics in transformed root cultures of Hyssopus officinalis [J].
Murakami, Y ;
Omoto, T ;
Asai, I ;
Shimomura, K ;
Yoshihira, K ;
Ishimaru, K .
PLANT CELL TISSUE AND ORGAN CULTURE, 1998, 53 (01) :75-78
[28]   METABOLIC ENGINEERING OF PLANT SECONDARY PRODUCTS [J].
NESSLER, CL .
TRANSGENIC RESEARCH, 1994, 3 (02) :109-115
[29]   Gene silencing mediated by promoter homology occurs at the level of transcription and results in meiotically heritable alterations in methylation and gene activity [J].
Park, YD ;
Papp, I ;
Moscone, EA ;
Iglesias, VA ;
Vaucheret, H ;
Matzke, AJM ;
Matzke, MA .
PLANT JOURNAL, 1996, 9 (02) :183-194
[30]   Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3′-hydroxylase (CYP80B1), a new methyl jasmonate-inducible cytochrome P-450-dependent mono-oxygenase of benzylisoquinoline alkaloid biosynthesis [J].
Pauli, HH ;
Kutchan, TM .
PLANT JOURNAL, 1998, 13 (06) :793-801