Solid-phase combinatorial synthesis of 2-arylquinazolines and 2-arylquinazolinones by an 4-alkoxyaniline linker

被引：19

作者：

Hioki, Hideaki ^{[1
]}

Matsushita, Kimihito ^{[1
]}

Nakamura, Shosei ^{[1
]}

Horiuchi, Hiroki ^{[1
]}

Kubo, Miwa ^{[1
]}

Harada, Kenichi ^{[1
]}

Fukuyama, Yoshiyasu ^{[1
]}

机构：

[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708514, Japan

来源：

JOURNAL OF COMBINATORIAL CHEMISTRY | 2008年 / 10卷 / 05期

关键词：

D O I：

10.1021/cc800056c

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

[No abstract available]

引用

页码：620 / 623

页数：4

共 27 条

[1] Synthesis of 5-substituted quinazolinone derivatives and their inhibitory activity in vitro [J].

Baek, DJ ;

Park, YK ;

Heo, HI ;

Lee, MH ;

Yang, ZY ;

Choi, MH .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (23) :3287-3290

[2] One pot synthesis of 4(3H)-quinazolinones [J].

Bhat, BA ;

Sahu, DP .

SYNTHETIC COMMUNICATIONS, 2004, 34 (12) :2169-2176

[3] Traceless solid-phase organic synthesis [J].

Blaney, P ;

Grigg, R ;

Sridharan, V .

CHEMICAL REVIEWS, 2002, 102 (07) :2607-2624

[4]

Bräse S, 2000, CHEM-EUR J, V6, P1899, DOI 10.1002/1521-3765(20000602)6:11<1899::AID-CHEM1899>3.0.CO

[5]

2-M

[6] Automated liquid-liquid extraction workstation for library synthesis and its use in the parallel and chromatography-free synthesis of 2-Alkyl-3-alkyl-4-(3H)-quinazolinones [J].

Carpintero, Mercedes ;

Cifuentes, Marta ;

Ferritto, Rafael ;

Haro, Ruben ;

Toledo, Miguel A. .

JOURNAL OF COMBINATORIAL CHEMISTRY, 2007, 9 (05) :818-822

[7] Substituted isoquinolines and quinazolines as potential antiinflammatory agents.: Synthesis and biological evaluation of inhibitors of tumor necrosis factor α [J].

Chao, Q ;

Deng, L ;

Shih, HC ;

Leoni, LM ;

Genini, D ;

Carson, DA ;

Cottam, HB .

JOURNAL OF MEDICINAL CHEMISTRY, 1999, 42 (19) :3860-3873

[8] Molecular-docking-guided design, synthesis, and biologic evaluation of radioiodinated quinazolinone prodrugs [J].

Chen, Kai ;

Al Aowad, Ayman F. ;

Adelstein, S. James ;

Kassis, Amin I. .

JOURNAL OF MEDICINAL CHEMISTRY, 2007, 50 (04) :663-673

[9] Synthesis of quinazolinones and quinazolines [J].

Connolly, DJ ;

Cusack, D ;

O'Sullivan, TP ;

Guiry, PJ .

TETRAHEDRON, 2005, 61 (43) :10153-10202

[10] Epidermal growth factor receptor tyrosine kinase: Structure-activity relationships and antitumour activity of novel quinazolines. [J].

Gibson, KH ;

Grundy, W ;

Godfrey, AA ;

Woodburn, JR ;

Ashton, SE ;

Curry, BJ ;

Scarlett, L ;

Barker, AJ ;

Brown, DS .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1997, 7 (21) :2723-2728

← 1 2 3 →