Highly enantioselective Friedel-Crafts reaction of indoles with imines by a chiral phosphoric acid

被引：375

作者：

Kang, Qiang ^{[1
]}

Zhao, Zhuo-An ^{[1
]}

You, Shu-Li ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 06期

关键词：

D O I：

10.1021/ja067417a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Highly enantioselective Friedel-Crafts reactions of indoles with imines catalyzed by a chiral phosphoric acid are developed, affording the 3-indolyl methanamine derivatives with up to > 99% ee for a wide range of substrates.

引用

页码：1484 / +

页数：3

共 31 条

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