BioProfiling.de: analytical web portal for high-throughput cell biology

被引:97
作者
Antonov, Alexey V. [1 ]
机构
[1] German Res Ctr Environm Hlth GmbH, Helmholtz Zentrum Munchen, Inst Bioinformat & Syst Biol, D-85764 Neuherberg, Germany
关键词
GENE ONTOLOGY; LISTS; PROTEIN; TOOL; SPIDER; KEGG; PATHWAYS; REACTOME; DATABASE; CONTEXT;
D O I
10.1093/nar/gkr372
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
BioProfiling.de provides a comprehensive analytical toolkit for the interpretation gene/protein lists. As input, BioProfiling.de accepts a gene/protein list. As output, in one submission, the gene list is analyzed by a collection of tools which employs advanced enrichment or network-based statistical frameworks. The gene list is profiled with respect to the most information available regarding gene function, protein interactions, pathway relationships, in silico predicted microRNA to gene associations, as well as, information collected by text mining. BioProfiling.de provides a user friendly dialog-driven web interface for several model organisms and supports most available gene identifiers. The web portal is freely available at http://www.BioProfiling.de/gene_list.
引用
收藏
页码:W323 / W327
页数:5
相关论文
共 27 条
  • [11] Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases
    Berger, Seth I.
    Posner, Jeremy M.
    Ma'ayan, Avi
    [J]. BMC BIOINFORMATICS, 2007, 8 (1)
  • [12] The Synergizer service for translating gene, protein and other biological identifiers
    Berriz, Gabriel F.
    Roth, Frederick P.
    [J]. BIOINFORMATICS, 2008, 24 (19) : 2272 - 2273
  • [13] Boutet Emmanuel, 2007, V406, P89
  • [14] CCancer: a bird's eye view on gene lists reported in cancer- related studies
    Dietmann, Sabine
    Lee, Wanseon
    Wong, Philip
    Rodchenkov, Igor
    Antonov, Alexey V.
    [J]. NUCLEIC ACIDS RESEARCH, 2010, 38 : W118 - W123
  • [15] Global functional profiling of gene expression
    Draghici, S
    Khatri, P
    Martins, RP
    Ostermeier, GC
    Krawetz, SA
    [J]. GENOMICS, 2003, 81 (02) : 98 - 104
  • [16] A systems biology approach for pathway level analysis
    Draghici, Sorin
    Khatri, Purvesh
    Tarca, Adi Laurentiu
    Amin, Kashyap
    Done, Arina
    Voichita, Calin
    Georgescu, Constantin
    Romero, Roberto
    [J]. GENOME RESEARCH, 2007, 17 (10) : 1537 - 1545
  • [17] Acid Elution and One-Dimensional Shotgun Analysis on an Orbitrap Mass Spectrometer: An Application to Drug Affinity Chromatography
    Fernbach, Nora V.
    Planyavsky, Melanie
    Mueller, Andre
    Breitwieser, Florian P.
    Colinge, Jacques
    Rix, Uwe
    Bennett, Keiryn L.
    [J]. JOURNAL OF PROTEOME RESEARCH, 2009, 8 (10) : 4753 - 4765
  • [18] Network pharmacology: the next paradigm in drug discovery
    Hopkins, Andrew L.
    [J]. NATURE CHEMICAL BIOLOGY, 2008, 4 (11) : 682 - 690
  • [19] KEGG: Kyoto Encyclopedia of Genes and Genomes
    Kanehisa, M
    Goto, S
    [J]. NUCLEIC ACIDS RESEARCH, 2000, 28 (01) : 27 - 30
  • [20] Profiling gene expression using onto-express
    Khatri, P
    Draghici, S
    Ostermeier, GC
    Krawetz, SA
    [J]. GENOMICS, 2002, 79 (02) : 266 - 270