Green alcohol couplings without transition metal catalysts: base-mediated β-alkylation of alcohols in aerobic conditions

被引：106

作者：

Allen, Laura J. ^{[1
]}

Crabtree, Robert H. ^{[1
]}

机构：

[1] Yale Univ, Dept Chem, New Haven, CT 06511 USA

来源：

GREEN CHEMISTRY | 2010年 / 12卷 / 08期

关键词：

SECONDARY ALCOHOLS; HYDROGEN-TRANSFER; COMPLEXES; IRIDIUM;

D O I：

10.1039/c0gc00079e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Benzylic secondary alcohols can be alkylated in good yields at the beta-position with primary alcohols promoted by KOH and NaOH, eliminating the need for toxic and expensive transition metal catalysts.

引用

页码：1362 / 1364

页数：3

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