Catalyst-free three-component reaction between 2-aminopyridines (or 2-aminothiazoles), aldehydes, and isocyanides in water

被引：117

作者：

Adib, Mehdi

Mahdavi, Mohammad

Noghani, Mahsa Alizadeh

Mirzaei, Peiman

机构：

[1] Univ Tehran, Univ Coll Sci, Sch Chem, Tehran, Iran

[2] Shahid Beheshti Univ, Dept Chem, Tehran, Iran

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 41期

关键词：

imidazo[1,2-a]pyridines; imidazo[2,1-b][1,3]thiazoles; isocyanides; three-component reactions; catalyst-free synthesis in water;

D O I：

10.1016/j.tetlet.2007.08.049

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A catalyst-free and convenient protocol is described for the preparation of 3-aminoimidazo[1,2-a]pyridines and 5-aminoimidazo[2,1-b][1,3]thiazoles via three-component reactions between 2-aminopyridines or 2-aminothiazoles, aldehydes, and isocyanides in water in good to excellent yields. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：7263 / 7265

页数：3

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