Microfluidic chips for cell sorting

被引：43

作者：

Chen, Pu ^{[1
]}

Feng, Xiaojun ^{[1
]}

Du, Wei ^{[1
]}

Liu, Bi-Feng ^{[1
]}

机构：

[1] Huazhong Univ Sci & Technol, Coll Life Sci & Technol, Dept Syst Biol,Hubei Bioinformat & Mol Imaging Ke, Div Biomed Photon,Wuhan Natl Lab Optoelect,Key La, Wuhan 430074, Peoples R China

来源：

FRONTIERS IN BIOSCIENCE-LANDMARK | 2008年 / 13卷

关键词：

microfluidics; lab-on-a-chip; cell sorting; mu FACS; review;

D O I：

10.2741/2859

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Micro total analysis systems (mu TAS) also referred to as "lab-on-a-chip" is one of the fastest progressing fields in biological and chemical analyses. In recent years, mu TAS for single cell analysis has drawn the attention of researchers due to its significant advantages over traditional methods for single cell manipulation, fast cell sorting and integration of multiple functions. As the preliminary step for studying cells on chips, cell sorting using microfluidics have been investigated by researchers intensively. This article reviews the most recent advances on microfuidics-based cell sorting techniques including cell sorting principle, strategy, mechanism and procedure with emphases on the sorting mechanism and procedure. Furthermore, evaluation criteria for successful cell sorter are also discussed and future research directions are given.

引用

页码：2464 / 2483

页数：20

共 115 条

[41] Micromachined electrochemical T-switches for cell sorting applications [J].