Research and development in biosensors

被引：199

作者：

Scheller, FW

Wollenberger, U

Warsinke, A

Lisdat, F

机构：

[1] Univ Potsdam, Inst Biochem & Biol, D-14476 Golm, Germany

[2] Univ Tokyo, Ctr Collaborat Res, Meguro Ku, Tokyo, Japan

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2001年 / 12卷 / 01期

关键词：

D O I：

10.1016/S0958-1669(00)00169-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Progress in biosensors has mainly been made by the improvement of the biological components and the implementation of microsystem technologies. Enzymes are still the most appropriate recognition elements because they combine high chemical specificity and inherent biocatalytic signal amplification. A breakthrough has been achieved in the application of membrane-integrated receptor systems for analyte recognition and signal transduction in biosensors. Sensor integration of RNA aptamers has been initiated, and the performance of fully synthetic molecularly imprinted polymers has been improved.

引用

页码：35 / 40

页数：6

共 55 条

[11] Antibodies in diagnostics - from immunoassays to protein chips [J].