Palladium-assisted routes to nucleosides

被引:397
作者
Agrofoglio, LA [1 ]
Gillaizeau, I [1 ]
Saito, Y [1 ]
机构
[1] Univ Orleans, CNRS, UMR 6005, Inst Chim Organ & Analyt, F-45067 Orleans, France
关键词
D O I
10.1021/cr010374q
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Over the past several years, explosive new developments have occurred in both palladium and nucleoside chemistry. As such, palladium cross-coupling reactions have found many potential application in the syntheses of nucleoside analogues used in antiviral or anticancer chemotherapy. The development of solid-phase palladium-catalyzed reactions, as well as the discovery of new applications of the C-N bond formation, will be of great value in exploring new families of nucleosides.
引用
收藏
页码:1875 / 1916
页数:42
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共 449 条
[61]  
COOKSON RC, 1985, EUR J MED CHEM, V20, P375
[62]   Synthesis of novel carbocyclic adenosine analogues as inhibitors of adenosine kinase [J].
Cowart, M ;
Bennett, MJ ;
Kerwin, JF .
JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (07) :2240-2249
[63]   An efficient, general asymmetric synthesis of carbocyclic nucleosides: Application of an asymmetric aldol/ring-closing metathesis strategy [J].
Crimmins, MT ;
King, BW ;
Zuercher, WJ ;
Choy, AL .
JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (25) :8499-8509
[64]   An efficient asymmetric approach to carbocyclic nucleosides: Asymmetric synthesis of 1592U89, a potent inhibitor of HIV reverse transcriptase [J].
Crimmins, MT ;
King, BW .
JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (13) :4192-4193
[65]   Solid-phase synthesis of carbocyclic nucleosides [J].
Crimmins, MT ;
Zuercher, WJ .
ORGANIC LETTERS, 2000, 2 (08) :1065-1067
[66]   New developments in the enantioselective synthesis of cyclopentyl carbocyclic nucleosides [J].
Crimmins, MT .
TETRAHEDRON, 1998, 54 (32) :9229-9272
[67]   Palladium-catalysed attachment of labels with acetylenic linker arms to biological molecules [J].
Crisp, GT ;
Gore, J .
TETRAHEDRON, 1997, 53 (04) :1523-1544
[68]   PALLADIUM-CATALYZED COUPLING OF URIDINE TRIFLATE WITH ORGANOSTANNANES [J].
CRISP, GT ;
FLYNN, BL .
TETRAHEDRON LETTERS, 1990, 31 (09) :1347-1350
[69]   PALLADIUM-CATALYZED COUPLING OF A PROPARGYLGLYCINE DERIVATIVE [J].
CRISP, GT ;
ROBERTSON, TA .
TETRAHEDRON, 1992, 48 (15) :3239-3250
[70]   PALLADIUM-CATALYZED COUPLING OF TERMINAL ALKYNES WITH 5-(TRIFLUOROMETHANESULFONYLOXY)PYRIMIDINE NUCLEOSIDES [J].
CRISP, GT ;
FLYNN, BL .
JOURNAL OF ORGANIC CHEMISTRY, 1993, 58 (24) :6614-6619