Continuous-Flow Syntheses of Heterocycles

被引：40

作者：

Glasnov, Toma N.

Kappe, C. Oliver ^{[1
]}

机构：

[1] Karl Franzens Univ Graz, CDLMC, A-8010 Graz, Austria

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2011年 / 48卷 / 01期

关键词：

BAEYER-VILLIGER OXIDATION; ORGANIC-SYNTHESIS; MULTISTEP SYNTHESIS; MICROREACTOR TECHNOLOGY; LOWEST CONCENTRATION; NATURAL-PRODUCT; SCALE-UP; REACTOR; DISCOVERY; CYCLOADDITIONS;

D O I：

10.1002/jhet.568

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This review surveys the synthesis of heterocycles under continuous-flow conditions, including the use of chip-based microreactors, coil-based flow reactors, and capillary or tubular devices.

引用

收藏

页码：11 / 30

页数：20

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共 94 条

[1] Heterogeneous Catalyzed Pyridine Synthesis using Montmorillionite and Nanoparticle-Impregnated Alumina in a Continuous Micro Flow System [J].

Abahmane, Lahbib ;

Knauer, Andrea ;

Ritter, Uwe ;

Koehler, J. Michael ;

Gross, G. Alexander .

CHEMICAL ENGINEERING & TECHNOLOGY, 2009, 32 (11) :1799-1805

[2] Microreactor technology:: Continuous synthesis of 1H-isochromeno[3,4-d]imidazol-5-ones [J].

Acke, Davy R. J. ;

Stevens, Christian V. ;

Roman, Bart I. .

ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2008, 12 (05) :921-928

[3] A HCN-based reaction under microreactor conditions:: industrially feasible and continuous synthesis of 3,4-diamino-1H-isochromen-1-ones [J].

Acke, Davy R. J. ;

Stevens, Christian V. .

GREEN CHEMISTRY, 2007, 9 (04) :386-390

[4] Advanced organic synthesis using microreactor technology [J].

Ahmed-Omer, Batoul ;

Brandt, Johan C. ;

Wirth, Thomas .

ORGANIC & BIOMOLECULAR CHEMISTRY, 2007, 5 (05) :733-740

[5] A simple continuous flow microwave reactor [J].

Bagley, MC ;

Jenkins, RL ;

Lubinu, MC ;

Mason, C ;

Wood, R .

JOURNAL OF ORGANIC CHEMISTRY, 2005, 70 (17) :7003-7006

[6] Fully automated continuous flow synthesis of 4,5-disubstituted oxazoles [J].

Baumann, Marcus ;

Baxendale, Ian R. ;

Ley, Steven V. ;

Smith, Christoper D. ;

Tranmer, Geoffrey K. .

ORGANIC LETTERS, 2006, 8 (23) :5231-5234

[7] Synthesis of 3-Nitropyrrolidines via Dipolar Cycloaddition Reactions Using a Modular Flow Reactor [J].

Baumann, Marcus ;

Baxendale, Ian R. ;

Ley, Steven V. .

SYNLETT, 2010, (05) :749-752

[8] A Bifurcated Pathway to Thiazoles and Imidazoles Using a Modular Flow Microreactor [J].

Baxendale, Ian R. ;

Ley, Steven V. ;

Smith, Christopher D. ;

Tamborini, Lucia ;

Voica, Ana-Florina .

JOURNAL OF COMBINATORIAL CHEMISTRY, 2008, 10 (06) :851-857

[9] A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly [J].

Baxendale, Ian R. ;

Deeley, Jon ;

Griffiths-Jones, Charlotte M. ;

Ley, Steven V. ;

Saaby, Steen ;

Tranmer, Geoffrey K. .

CHEMICAL COMMUNICATIONS, 2006, (24) :2566-2568

[10] Multi-Step Synthesis by Using Modular Flow Reactors: The Preparation of Yne-Ones and Their Use in Heterocycle Synthesis [J].

Baxendale, Ian R. ;

Schou, Soren C. ;

Sedelmeier, Joerg ;

Ley, Steven V. .

CHEMISTRY-A EUROPEAN JOURNAL, 2010, 16 (01) :89-94

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