PomBase: a comprehensive online resource for fission yeast

被引:228
作者
Wood, Valerie [1 ,2 ,3 ]
Harris, Midori A. [1 ,2 ]
McDowall, Mark D. [4 ]
Rutherford, Kim [1 ,2 ]
Vaughan, Brendan W. [4 ]
Staines, Daniel M. [4 ]
Aslett, Martin [5 ]
Lock, Antonia [6 ,7 ]
Baehler, Juerg [6 ,7 ]
Kersey, Paul J. [4 ]
Oliver, Stephen G. [1 ,2 ]
机构
[1] Univ Cambridge, Cambridge Syst Biol Ctr, Cambridge CB2 1GA, England
[2] Univ Cambridge, Dept Biochem, Cambridge CB2 1GA, England
[3] London Res Inst, Cell Cycle Lab, Canc Res UK, London WC2A 3LY, England
[4] European Bioinformat Inst, Hinxton CB10 1SD, Cambs, England
[5] Wellcome Trust Sanger Inst, Hinxton CB10 1SA, Cambs, England
[6] UCL, Dept Genet Evolut & Environm, London WC1E 6BT, England
[7] UCL, UCL Canc Inst, London WC1E 6BT, England
基金
英国惠康基金;
关键词
ONTOLOGY; SEQUENCE; ENSEMBL; ARTEMIS;
D O I
10.1093/nar/gkr853
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
PomBase (www.pombase.org) is a new model organism database established to provide access to comprehensive, accurate, and up-to-date molecular data and biological information for the fission yeast Schizosaccharomyces pombe to effectively support both exploratory and hypothesis-driven research. PomBase encompasses annotation of genomic sequence and features, comprehensive manual literature curation and genome-wide data sets, and supports sophisticated user-defined queries. The implementation of PomBase integrates a Chado relational database that houses manually curated data with Ensembl software that supports sequence-based annotation and web access. PomBase will provide user-friendly tools to promote curation by experts within the fission yeast community. This will make a key contribution to shaping its content and ensuring its comprehensiveness and long-term relevance.
引用
收藏
页码:D695 / D699
页数:5
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