The plant N-end rule pathway: structure and functions

被引:75
作者
Graciet, Emmanuelle [1 ]
Wellmer, Frank [1 ]
机构
[1] Trinity Coll Dublin, Smurfit Inst Genet, Dublin 2, Ireland
基金
爱尔兰科学基金会;
关键词
RNA-PROTEIN TRANSFERASE; UBIQUITIN FUSION TECHNIQUE; POLAR AUXIN TRANSPORT; RECOGNITION COMPONENT; ARABIDOPSIS-THALIANA; DEGRADATION SIGNALS; ESCHERICHIA-COLI; EFFECTOR AVRRPT2; TERMINAL AMIDASE; GENE;
D O I
10.1016/j.tplants.2010.04.011
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The N-end rule pathway is a protein degradation pathway that relates the stability of a protein to the nature of its N-terminal amino acid residue. This pathway is part of the ubiquitin-proteasome system in eukaryotes and has been shown to be involved in a multitude of cellular and developmental processes in animals and fungi. However, in plants, its structure and functions have long been enigmatic. In this review, we discuss recent advances in the identification of the enzymatic components that mediate protein degradation through the N-end rule pathway in plants. We further describe the known functions of this pathway in the control of plant growth and development and outline open questions that will likely be the focus of future research.
引用
收藏
页码:447 / 453
页数:7
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